HUBUNGAN BEBAN KERJA MENTAL DENGAN DEPRESI DAN CEMAS PADA PERAWAT ICU-NICU-PICU DI RS MITRA SEJATI

ANTIBACTERIAL EFFECTIVENESS OF TURMERIC RHIZOME ETHANOL EXTRACT (CURCUMA DOMESTICA VAL) AGAINST VIBRIO CHOLERAE GROWTH IN VITRO

  • Arneil Sitepu Institut Kesehatan Deli Husada Deli Tua
  • Muhraza Siddiq Institut Kesehatan Deli Husada Deli Tua
  • Nurul Aini Siagian Institut Kesehatan Deli Husada Deli Tua
Keywords: Beban Kerja Mental, Depresi, Kecemasan, Perawat, Unit Perawatan Intensif

Abstract

Vibrio cholerae is a Gram-negative, anaerobic bacterium. Cholera is an intestinal infection caused by Vibrio cholerae or contact with a cholera carrier. Turmeric rhizome (Curcuma domestica Val) extract is known to have antibacterial properties. Active compounds such as flavonoids, saponins, alkaloids, and tannins in turmeric rhizomes have been shown to inhibit the growth of Vibrio cholerae. This study aimed to evaluate the antibacterial effectiveness of turmeric rhizome extract (Curcuma domestica Val) against the growth of Vibrio cholerae in vitro. The research used a descriptive approach with experimental methods, conducted at the Microbiology and Organic Chemistry Laboratory, University of Sumatera Utara (USU). Extraction was performed using the maceration method. The study employed four different concentrations of turmeric rhizome extract: 25%, 50%, 75%, and 100%. Data collection involved treating Vibrio cholerae cultures with the extracts and measuring the diameter of the inhibition zones using a caliper. Data analysis was conducted using ANOVA and a Post Hoc Bonferroni test. Results showed that the 100% concentration of turmeric rhizome extract was the most effective in inhibiting the growth of Vibrio cholerae, with a p-value of 0.000, an average inhibition zone diameter of 22.2 ± 0.49 mm, and a categorization of "susceptible" response.

 

Abstrak
Penelitian ini mengeksplorasi hubungan antara beban kerja mental dengan tingkat depresi dan kecemasan pada perawat di unit ICU dan NICU-PICU di RS Mitra Sejati. Metode penelitian menggunakan desain deskriptif kuantitatif dengan pendekatan analitik. Sampel terdiri dari 44 perawat yang diambil secara total sampling. Instrumen meliputi kuesioner untuk mengukur beban kerja mental, tingkat depresi, dan kecemasan. Analisis statistik menunjukkan bahwa sebagian besar perawat di ICU dan NICU-PICU memiliki beban kerja mental tinggi hingga sangat tinggi, dengan tingkat depresi dan kecemasan berat. Namun, uji korelasi spearman mengungkapkan bahwa beban kerja mental tidak memiliki hubungan signifikan dengan tingkat depresi (ρ=0,796) atau kecemasan (ρ=0,797). Hasil ini mengindikasikan adanya faktor lain, seperti dukungan sosial dan strategi coping, yang dapat memoderasi dampak beban kerja mental. Penelitian ini merekomendasikan pendekatan holistik untuk mengelola beban kerja, termasuk penguatan dukungan sosial dan program pengurangan stres untuk meningkatkan kesejahteraan perawat.

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Published
2025-01-01
How to Cite
Sitepu, A., Siddiq, M., & Siagian, N. A. (2025). HUBUNGAN BEBAN KERJA MENTAL DENGAN DEPRESI DAN CEMAS PADA PERAWAT ICU-NICU-PICU DI RS MITRA SEJATI: ANTIBACTERIAL EFFECTIVENESS OF TURMERIC RHIZOME ETHANOL EXTRACT (CURCUMA DOMESTICA VAL) AGAINST VIBRIO CHOLERAE GROWTH IN VITRO. Jurnal Kedokteran STM (Sains Dan Teknologi Medik), 8(1), 72-79. https://doi.org/10.30743/stm.v8i1.819
Section
Artikel Penelitian